Time

Meetings

Room

9:00

TIAFT Young Scientists Symposium

Lecture Hall I, ground floor

9:00

TIAFT Executive Board Meeting

Dozenten-zimmer,
1^st floor

11:30

TIAFT Regional Representatives Meeting

Seminar room No. 1, 2^nd floor

12:30

Lunch for Young Scientists and TIAFT Board

Cafeteria

14:00

TIAFT Young Scientists Committee Meeting

Dozenten-zimmer,
1^st floor

14:00

TIAFT STA Committee Meeting

Seminar room No. 1, 2^nd floor

14:00

TIAFT Internet Committee Meeting

Seminar room No. 3, 2^nd floor

18:00

Opening Ceremony

Aula,
1^st floor

20:00

Welcome Reception

sponsored by
Agilent Technologies

Festsaal and Senatssaal,
1^st floor

8:00

Registration, Posters, Exhibition
(Internet Café sponsored by LGC)

Foyer and
Connected Rooms

8:30

Topic: Alcohol, Drugs and Driving I

Chairs: Alan Wayne Jones, Aldo Polettini

8:30

O-1

Detection and validated quantification ethylglucuronide and ethylsulfate in human urine

Jochen Beyer, Tu N. Vo, Dimitri Gerostamoulos, Olaf Drummer

8:42

O-2

Detection time of direct alcohol markers, ethyl glucuronide (EtG) and ethyl sulfate (EtS), in oral fluid and urine after dosing to 0.08%

Christine Moore, Paul Marques, Cynthia Coulter

8:54

O-3

Incidence of post-collection synthesis and hydrolysis of ethyl glucuronide (EtG) and ethyl sulfate (EtS) in random unpreserved urine specimens

Sumandeep Rana, Wayne Ross

9:06

O-4

Distribution of phosphatidylethanol homologues determined by LC-ESI-MS/MS and comparison to CDT during withdrawal therapy

Heike Gnann, Claudia Engelmann, Annette Thierauf, Gisela Skopp, Michaela Winkler, Frank Sporkert, Wolfgang Weinmann

9:18

O-5

A targeted lipidomic approach for the LC-HRMS quantitation of phosphatidylethanol molecular species in human blood

Alessandro Nalesso, Guido Viel, Giovanni Cecchetto, Massimo Montisci, Donata Favretto, Santo Davide Ferrara

9:30

O-6

Comparison of blood ethanol concentration and breath ethanol concentration in practice

Marc Augsburger, Frank Sporkert, Patrice Mangin

9:42

O-7

Prevalence of drugs of impairment in oral fluid from random roadside testing

Mark Chu, Dimitri Gerostamoulos, Jochen Beyer, Martin Boorman, Olaf Drummer

10:00

Coffee Break, Posters, Exhibition

10:45

Topic: Alcohol, Drugs and Driving II

Chairs: Alain Verstraete, Nele Samyn

10:45

O-8

The extent of drug-associated driving in Victoria

Olaf Drummer, Irene Kourtis, Jochen Beyer, Martin Boorman, Dimitri Gerostamoulos

10:57

O-9

Significant increased detection rate of drugs of abuse in urine following the introduction of new German driving licence re-granting guidelines

Ronald Agius, Thomas Nadulski, Hans-Gerhard Kahl, Bertin Dufaux

11:09

O-10

Influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users

Stefan W. Toennes, Kirsten Schneider, Gerold F. Kauert, Cora Wunder, Manfred R. Moeller, Wendy Bosker, Eef L. Theunissen, Jan G. Ramaekers

11:21

O-11

Stability of cannabinoids in plasma and whole blood of authentic specimens

Bertrand Brunet, Adeline Ane, Yves Papet, Patrick Mura

11:33

O-12

?9-Tetrahydrocannabinolic acid A in hair - a novel marker for external contamination with cannabis smoke

Volker Auwärter, Ariane Wohlfarth, Jessica Traber, Detlef Thieme, Wolfgang Weinmann

11:45

O-13

A liquid chromatography–high resolution mass spectrometry method for the simultaneous determination of 30 benzodiazepines and metabolites in hair

Susanna Vogliardi, Donata Favretto, Marianna Tucci, Alessandro Nalesso, Rita Frassanito, Santo Davide Ferrara

11:57

O-14

Detection and validated quantification of 21 benzodiazepines/metabolites and 3 “Z-Drugs” in human hair by LC-MS/MS

Kristina Y. Rust, Markus R. Baumgartner, Natascha Meggiolaro, Thomas Kraemer

12:15

Lunch Break, Posters, Exhibition

13:15

-14:00

Siemens Vendor Seminar (Studio)

14:15

Topic: Drug Facilitated Crime

Chairs: Marc LeBeau, Simon Elliott

14:15

O-15

Drug facilitated crime ("DFC") using tetrazepam

Frédéric Aknouche, Thierry Besnard, Robert Buti, Henri-Pierre Duval

14:27

O-16

Determination of clonazepam and 7-aminoclonazepam in hair after a single intake by HPLC-ESI-MS-MS. Application to forensic case of drug facilitated crime

Sebastian Rojek, Ma?gorzata K?ys

14:39

O-17

Hair analysis in a suspected rape case involving zolpidem

Alberto Salomone, Daniele Di Corcia, Enrico Gerace, Marco Vincenti, Michele Petrarulo

14:51

O-18

Disposition of ketamine and its metabolites in hair after a single dose

Ping Xiang, Qiran Sun, Baohua Shen, Min Shen

15:03

O-19

The role of variations in growth rate and sample collection on interpreting results of segmental analyses of hair

Marc LeBeau, Madeline Montgomery, Jason Brewer

15:15

O-20

Measurement uncertainty in quantitative segmental analysis of hair for amphetamine and methamphetamine

Madeline Montgomery, Marc LeBeau, Cynthia Morris-Kukoski, Jason Schaff, Marc LeBeau

15:27

O-21

Drug and alcohol facilitated sexual assault litigation

Michael Smith, David Lesser, John Jemionek, Eric Shimomura, Timothy Lyons

15:45

Coffee Break, Posters, Exhibition

16:30

Topic: Extraction Techniques and Matrix Effects

Chairs: Olof Beck, Thomas Stimpfl

16:30

O-22

A new “Dilute and Shoot” method for the detection and quantification of more than 50 drugs of abuse and their metabolites for quick routine analysis in urine, serum, and hair via LC-MS/MS

David Bassan, Ralf Krüll, Heike Wollersen, Freidoon Erdmann

16:42

O-23

Application of molecularly imprinted solid phase extraction (MISPE) and liquid chromatography tandem mass spectrometry (LC-MS/MS) to the detection of amphetamines in whole blood

Norlida Harun, Robert, A Anderson

16:54

O-24

Fully automated offline sample preparation - from whole blood to injection-ready samples with a single mouse click

Brian Schou Rasmussen, Kristian Linnet

17:06

O-25

Rapid quantification of tilidine, nortilidine and bisnortilidine in urine by automated online-SPE-LC-MS/MS

Christoph Köhler, Thomas Grobosch, Torsten Binscheck

17:18

O-26

Automated SPE-LC-MS-MS analysis of codeine, morphine, oxycodone, oxymorphone, hydrocodone, and hydromorphone in human urine specimens: application for a high-throughput urinalysis laboratory

Paul Robandt, Huong Bui, Kevin Klette

17:30

O-27

Development and validation of a library-assisted toxicological screening system using online extraction

Daniel Mueller, Katharina Rentsch

17:42

O-28

Comparison of ion suppression and enhancement effects of co-eluting analytes in a LC-MS/MS multi-analyte procedure using APCI and ESI

Daniela Remane, Markus R. Meyer, Dirk K. Wissenbach, Hans H. Maurer

18:00

Wine and Cheese Reception in Exhibition

sponsored by Waters

8:00

Registration, Posters, Exhibition,
(Internet Café sponsored by LGC)

Foyer and
Connected Rooms

8:30

Topic: Analytical Toxicology

Chairs: Franco Tagliaro, Dimitri Gerostamoulos

8:30

O-29

Determination of tetramine concentrations in hair: A case study

Min Shen, Ping Xiang

8:42

O-30

Glucarpidase – an investigational agent for patients with toxic MTX blood levels or reduced MTX clearance

Thomas Grobosch, Lars Ambach, Torsten Binscheck

8:54

O-31

Analysis of phenol in blood by GC-MS

Chia Han Lin, Bud-Gen Chen, Ray H. Liu, Chin-Hsing Lai, Thomas J. H. Chen, Wen-Yi Lin, Yee-Lin Wu, Shiv D. Kumar

9:06

O-32

Analysis of drugs of abuse in hair: Evaluation of the immunochemical method VMA-T vs. LC-MS/MS

Markus Baumgartner, Rosetta Guglielmello, Monique Fanger, Thomas Kraemer

9:18

O-33

Method validation of a survey of thevetia cardiac glycosides in serum samples

Sarah Kohls, Barbara Scholz-Böttcher, Jürgen Rullkötter, Jörg Teske

9:30

O-34

Chiral analyses of dextromethorphan/levomethorphan and their metabolites in rat and human samples using LC-MS/MS

Ruri Kikura-Hanajiri, Maiko Kawamura, Atsuko Miyajima, Momoko Sunouchi, Yukihiro Goda

9:42

O-35

Development and validation of a highly sensitive UFLC-MS/MS method for the analysis of fentanyl and its major metabolite norfentanyl in urine and whole blood in forensic context

Ruth Verplaetse, Jan Tytgat

10:00

Coffee Break, Posters, Exhibition

10:45

Topic: Drug Metabolism and Kinetics

Chairs: Marilyn Huestis, Marta Concheiro

10:45

O-36

Degradation kinetics and detection windows of succinylcholine and succinylmonocholine in serum and urine for forensic-toxicological applications

Uta Kuepper, Frank Musshoff, Frank Herbstreit, Ralf A. Hilger, Burkhard Madea

10:57

O-37

Investigation of in vitro phase I metabolites of the synthetic cannabinomimetic JWH-018

Annette Wintermeyer, Ines Moeller, Mario Thevis, Martin Juebner, Justus Beike, Markus A. Rothschild, Katja Bender

11:09

O-38

Identification of the main metabolites of JWH-018, an active ingredient of K2 (Fake Weed) in human urine

Sumandeep Rana, Jeremiah Morris, Wayne Ross, Alexandre Wang, Matthew Clabaugh, Hua-fen Liu

11:21

O-39

Monitoring of Kratom alkaloids and its metabolites in urine using LC-Linear Ion Trap-MSn and GC-MS

Anika-Anina Philipp, Dirk K. Wissenbach, Armin A, Weber, Josef Zapp, Siegfried W. Zoerntlein, Jidapha Kanogsunthornrat, Peter G. M. Zweipfenning, Hans H. Maurer

11:33

O-40

Phase-II metabolism of MDMA: Sulfation kinetics of DHMA and HMMA and their capability to inhibit human sulfotransferases

Andrea E. Schwaninger, Markus R. Meyer, Hans H. Maurer

11:45

O-41

Studies on the metabolism of the alpha-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV) using GC-MS and LC-high-resolution-MS and its detectability in urine

Markus R. Meyer, Peng Du, Frank Schuster, Hans H. Maurer

11:57

O-42

Cocktail approach for phenotyping of five major CYP450 isoenzymes: methodology and pilot test

Ariane Wohlfarth, Sebastian Dresen, Wolfgang Weinmann, Volker Auwärter

12:15

Lunch Break, Posters, Exhibition

13:15

-14:00

Waters Vendor Seminar (Studio)

14:15

Topic: Hormones in Doping Control and Forensics

Chairs: Detlef Thieme, Johan Ahlner

14:15

O-43

Anabolic steroid adverse findings among specific population groups in the United States: classic vs. designer drugs

Victor Uralets

14:27

O-44

Anabolic androgenic steroids in police cases in Sweden 1999-2009

Yvonne Lood, Arne Eklund, Johan Ahlner

14:39

O-45

Steroid concentrations in brain and potential psychiatric effects

Detlef Thieme, Claudia Rautenberg, Sybille Fieseler

14:51

O-46

Determination of human insulin and its synthetic analogues in human plasma by electrospray ionization liquid chromatography/tandem mass spectrometry

Cornelius Hess, Frank Musshoff, Andreas Thomas, Mario Thevis, Burkhard Madea

15:03

O-47

Screening for urinary insulin and other bioactive peptides by nanoUPLC-MS/MS for doping control purposes

Andreas Thomas, Maxie Kohler, Wilhelm Schänzer, Mario Thevis

15:15

O-48

Selective androgen receptor modulators in sports drug testing

Mario Thevis, Enrico Gerace, Simon Beuck, Andreas Thomas, Wilhelm Schänzer

15:27

O-49

In-vitro metabolism of the PPAR-delta agonist GW1516 and implementation of its major metabolites in routine doping controls

Ines Möller, Andreas Thomas, Simon Beuck, Grigory Rodchenkov, Wolfgang Bornatsch, Hans Geyer, Wilhelm Schänzer, Mario Thevis

15:45

Coffee Break, Posters, Exhibition

16:30

Topic: Alternative Matrices

Chairs: Carmen Jurado, Madeline Montgomery

16:30

O-50

MDMA and metabolite disposition in expectorated oral fluid following controlled oral MDMA administration

Allan Barnes, Erin Kolbrich-Spargo, Karl Scheidweiler, David Gorelick, Robert Goodwin, Marilyn A. Huestis

16:42

O-51

Determination of endogenous gamma-hydroxybutyric acid (GHB) levels in saliva by gas chromatography–mass spectrometry: last piece of the puzzle for GHB

Giorgia De Paoli, Katrina M. Walker, Derrick J. Pounder

16:54

O-52

Simultaneous analysis of buprenorphine, methadone, cocaine, opiates, nicotine, and metabolites in sweat by liquid chromatography tandem mass spectrometry

Marta Concheiro, Diaa M. Shakleya, Marilyn A. Huestis

17:06

O-53

Drug analysis of human tears by liquid chromatography coupled to tandem mass spectrometry

Thierry Besnard, Frédéric Aknouche, Jacques Chofflet, Henri-Pierre Duval

17:18

O-54

Comprehensive drug screening of meconium

Johanna Ristimaa, Merja Gergov, Anna Pelander,Ilkka Ojanperä

17:30

O-55

Correlations for maternal methadone dose, placental methadone and EDDP concentrations, and neonatal outcomes

Ana de Castro, Diaa Shakleyaa, Rolley Johnson, Robin Choo, Hendreé Jones, Marilyn A. Huestis

17:42

O-56

Drug testing using exhaled breath? Demonstration of a new possibility in toxicology

Olof Beck

18:00

Agilent Technologies Vendor Seminar (Studio)

8:00

Registration, Posters, Exhibition
(Internet Café sponsored by LGC)

Foyer and
Connected Rooms

8:30

Topic: Postmortem Toxicology I

Chairs: Dan Isenschmid, Helena Teixeira

8:30

O-57

Determination of ketone bodies in blood by HS/GC/MS

Karen Jørgensen, Kristian Linnet, Brian Rasmussen, Anders Pedersen

8:42

O-58

Evaluation of the Randox whole blood Drugs of Abuse Array I for the analysis of alternative postmortem toxicology samples

Poppy McLaughlin, Derrick Pounder, David Osselton

8:54

O-59

Combined use of LC-QTOF-MS and HPLC-DAD in systematic toxicological analysis

Fritz Pragst, Sebastian Broecker, Abdulsallam Bakdash, Sieglinde Herre, Michael Tsokos

9:06

O-60

Screening for benzodiazepines and antipsychotics in post mortem blood using LC-QTOF in automated MSMS mode

Peter Stockham, Sheridan Martin, Claire Lenehan, Chris Fouracre, Peter Felgate

9:18

O-61

MALDI mass spectrometric imaging in tissue sections as a new tool in forensic toxicology

Tiffany Porta, Emmanuel Varesio, Gérard Hopfgartner, Thomas Kraemer

9:30

O-62

Stability of antipsychotic drugs in stored blood samples

Eva Saar, Dimitri Gerostamoulos, Jochen Beyer, Olaf H. Drummer

9:42

O-63

Stability of selected prescription drugs during decomposition

Danielle Butzbach, Roger Byard, Hilton Kobus, D. Noel Sims, Peter Stockham, Robert Lokan, G. Stewart Walker

9:54

O-64

The effect of the postmortem interval on the redistribution of 52 drugs: A comparison of admission and autopsy blood specimens

Dimitri Gerostamoulos, Jochen Beyer, Voula Staikos, Penny Tayler, Olaf Drummer

10:06

O-65

Strategy to demonstrate external post mortem contamination of hair: place of segmental analysis

Pascal Kintz

10:20

Coffee Break, Posters, Exhibition

11:15

Topic: Postmortem Toxicology II

Chairs: Olaf Drummer, Robert Kronstrand

11:15

O-66

Incidence of ethanol and drug consumption in fatal accidents at the workplace

Carmen Jurado, Mª Paz Gimenez, Luisa Escobar, Rosario Garcia-Repetto, Agustin Gonzalez, Esperanza Moreno, David Olano, Carmen Pareja, Angeles Pérez, Ana del Peso, Isabel Rodríguez, Luisa Salas, Teresa Soriano, Mª Luisa Soria

11:27

O-67

Drug poisoning deaths in Sweden show a predominance of ethanol in mono-intoxications, adverse drug-alcohol interactions and poly-drug abuse

Alan Wayne Jones, Anita Holmgren, Fredrik Kugelberg, Johan Ahlner

11:39

O-68

Smoking is associated with alcohol, drugs of abuse and psychopharmaceuticals – A post-mortem database study in young adults

Terhi Launiainen, Ilkka Ojanperä

11:51

O-69

Serotonin toxicity involving MDMA and moclobemide

Jennifer L Pilgrim, Dimitri Gerostamoulos, Olaf H Drummer

11:03

O-70

Reporting a sudden death due to accidental gasoline inhalation

María Antonia Martínez, Salomé Ballesteros, Rafael Alcaraz

12:15

O-71

Cerbera manghas vs. Birgus latro: where is the poison coming from? A case report

Marc Deveaux, Marjorie Cheze, Yann Barguil, Michel Maillaud, Carole Leleu, Guillaume Hoizey, Gilbert Pepin

12:27

O-72

Fatality with controlled release morphine

Ashraf Mozayani, Terry Danielson

12:39

O-73

The role of dihydrocodeine metabolites in dihydrocodeine related deaths

Ahmed Al-Asmari, Robert Anderson

12:51

O-74

Interpretation of opiate concentrations in post-mortem brain samples of heroin users

Cora Wunder, Jana Czoelder, Kettner Matthias, Peter Schmidt, Stefan W. Toennes

8:30

Topic: Forensic Chemistry

Chairs: Heesun Chung, Osamu Suzuki

8:30

O-75

The use of gas chromatographic isotope ratio mass spectrometry for cannabis profiling

Yuko Iwata, Hiroyuki Inoue, Kenji Kuwayama, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Hirofumi Fukushima

8:42

O-76

Comparison of ‘legal highs’ composition

Bogumila Byrska, Martyna Maciów, Dariusz Zuba

8:54

O-77

Identification of cathinone-derivatives in a „bath salt“ and a „glass surface protector“ – are these new ways to deal with drugs?

Andreas Ewald, Thomas Kraemer, Jochen Wilske

9:06

O-78

Acute poisoning involving the pyrrolidinophenone-type designer drug 4‘-methyl-alpha-pyrrolidinohexanophenone (MPHP)

Christoph Sauer, Kerstin Hoffmann, Polina Mattis, Frank T Peters

9:20

Coffee Break (Bundeshaus Foyer)

10:20

Topic: Alcohol Markers in Hair

Chairs: Fritz Pragst, Michele Yegles

10:20

O-79

Epidemiological evaluation of ethylglucuronide levels in different keratinic matrices

Valentina Pirro, Daniele Di Corcia, Sergio Pellegrino, Marco Vincenti, Alberto Salomone

10:32

O-80

Incorporation of ethyl glucuronide into rat hair as function of ethanol dose and hair pigmentation

Frank Sporkert, Hicham Kharbouche, Christian Staub, Patrice Mangin, Marc Augsburger

10:44

O-81

Ethyl glucuronide in hair after abstinence and low alcohol consumption. A controlled study in 44 subjects

Robert Kronstrand, Linda Brinkhagen, Fredrik Nystrom

10:56

O-82

Comparison of the ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) concentrations in hair for testing abstinence

Maria Elena Albermann, Frank Musshoff, Burkhard Madea

11:08

O-83

Impact of hair-care products on FAEE hair concentrations in substance abuse monitoring

Joey Gareri, Brice Appenzeller, Gideon Koren

11:20

Lunch Break (Bundeshaus Foyer)

12:30

- 13:15

Thermo Fisher Vendor Seminar (Plenary Chamber)

13:30

Topic: Recent Developments in LC-MS Screening

Chairs: Willy Lambert, Ilkka Ojanpera

13:30

O-84

High resolving power time-of-flight mass spectrometry in drug screening: preliminary evaluation

Anna Pelander, Petra Decker, Carsten Baessmann, Ilkka Ojanperä

13:42

O-85

Differentiation of isomers by LC/Q-TOFMS using fragmentation prediction

Elli Tyrkkö, Anna Pelander, Ilkka Ojanperä

13:54

O-86

LC-TOF-based toxicological drug screening: a chemometric approach

Aldo Polettini, Eloisa Liotta, Anna Bertaso, Rossella Gottardo

14:06

O-87

Metabolite-based LC-MS urine screening using Linear Ion Trap technology, exemplified for antidepressants

Dirk K. Wissenbach, Daniela Remane, Markus R. Meyer, Hans H. Maurer

14:18

O-88

General unknown screening in hair by LC-QTOF-MS

Sebastian Broecker, Fritz Pragst

14:30

Closing Ceremony (Plenary Chamber)

14:30

History of the German Bundestag

15:00

Closing Remarks

15:15

Business Meeting (Plenary Chamber)

20:00

Reception and Farewell Banquet (Maritim Hotel)

sponsored by Thermo Fisher Scientific

Topic: Alcohol, Drugs and Driving

P-1

Specific measurement of ethanol in serum and urine with an assay kit on the fully automated RX series analysers

P. McGivern, T. Lipton, R. I. Bell, J. Campbell, S. P. Fitzgerald

P-2

Alcohol and drugs in fatal road accidents between 1999 and 2009

Cristiana Stramesi, Claudia Vignali, Maria Luisa Fino, Angelo Groppi

P-3

The effects of reducing the legal blood alcohol concentration limit for driving in Sao Paulo, Brazil

Gabriel Andreuccetti, Heraclito Barbosa Carvalho, Cheryl Cherpitel, Julio Carvalho Ponce, Vilma Leyton, Tulio Kahn

P-4

Self reported (il)licit drug use in Belgian drivers

Trudy Van der Linden, Peter Silverans, Cristina Isalberti, Sara-Ann Legrand, Alain Verstraete

P-5

Analytical evaluation of five oral fluid drug testing devices

Cristina Isalberti, Sylvie Vanstechelman, Sara-Ann Legrand, Trudy Van der Linden, Alain Verstraete

P-6

Prevalence of alcohol, drugs and benzodiazepines among drivers and pedestrians involved in road accidents in the South Region of Portugal during the years 2008 - 2009

Nuno Gonçalves, Susana Fonseca, Mário Dias

P-7

Amphetamines, cocaine and cannabinoids use among truck drivers in the roads of the State of Sao Paulo, Brazil

Vilma Leyton, Daniele Mayumi Sinagawa, Keziah Cristina Barbosa Gruber de Oliveira, Wagner Schmitz, Gabriel Andreuccetti, Bruno Spinosa De Martinis, Daniel Romero Munoz

P-8

Alcohol and psychoactive substance related road traffic injuries in Pakistan

Ajmal Khan Khoso

Topic: Drug Facilitated Crime

P-9

Use of hydrophilic interaction liquid chromatography–tandem mass spectrometry for fast determination of gamma-hydroxybutyrate (GHB) in plasma and urine

Jose Luiz Costa, Rafael Lanaro

P-10

In vitro production of GHB in untreated blood and serum samples under varied storage conditions

Siegfried W. Zoerntlein, Alexandra Kopp, Juergen Becker, Thomas J. Kaufmann, Joerg Roehrich, Reinhard Urban

P-11

GHB in hair - a mathematical approach to the evaluation of a possibly positive case

Klaas J. Lusthof, Ingrid J. Bosman

P-12

GBL as counterfeit wine for date-rape

C. Tangbanluekal, T. Sinchai, P. Suteerakune

P-13

Sexual abuse and anti-wrinkle cream : evidence from octocrylene

Carole Jamey, Antoine Tracqui, Bertrand Ludes

Topic: Extraction Techniques

P-14

Comparison of the efficiency of extraction procedures in post-mortem multi-target GC-MS screening for prevalent drugs in Hungary

Elod Hidvegi, Agnes Kerner, Agnes Ruff, Peter Fabian, Gabor Pal Somogyi

P-15

Application of a non-conditioning solid-phase extraction method for determination of opiates in human urine by GC-MS

Fotini Athanasiadou, Konstantina Spagou, Georgios Theodoridis, Nikolaos Raikos, Helen Gika, Tsoukali Helen

P-16

Automated solid-phase extraction procedure for body fluids and tissue samples

Thomas Stimpfl

P-17

Extraction of THC and metabolites from urine and plasma using supported liquid extraction (SLE) prior to LC-MS/MS analysis

Rhys Jones, Lee Williams, Helen Lodder, Steve Jordan, Steve Plant, Richard Calverley, Claire Desbrow, Gary Dowthwaite

P-18

Extraction of cocaine and metabolites using resin-based mixed-mode cation exchange SPE with LC-MS/MS analysis

Rhys Jones, Lee Williams, Helen Lodder, Steve Jordan, Steve Plant, Richard Calverley, Claire Desbrow, Gary Dowthwaite

P-19

Mephedrone: evaluation of extraction using mixed-mode cation exchange SPE with LC-MS/MS analysis

Rhys Jones, Lee Williams, Helen Lodder, Steve Jordan, Steve Plant, Richard Calverley, Claire Desbrow, Gary Dowthwaite

P-20

First experiences with automated on-line SPE-LC-QqTOF for the use in systematic toxicological analysis

Christoph Köhler, Thomas Grobosch, Torsten Binscheck

P-21

Quantification of THC, 11-OH-THC and THC-COOH in whole blood by on-line extraction - liquid chromatography tandem mass spectrometry

Stefan König, Stephan Lanz, Martina Gasser, Beat Aebi, Wolfgang Weinmann

P-22

Analysis of cocaine, ecstasy, 6-acetylmorphine and buprenorphine in human plasma and urine by online extraction TurboFlow™– Mass spectrometry

Samuele Scurati, Cecilia Gechtman, Benedict Duretz, Sarah Robinson, Adriano Masarin

P-23

Analysis of THC and THC-COOH in plasma and urine using online extraction LC-MS/MS

Samuele Scurati, Cecilia Gechtman, Benedict Duretz, Sarah Robinson, Adriano Masarin

P-24

Analysis of clozapine and norclozapine in plasma using automated sample preparation and LC-MS/MS

Phillip Morgan,Sarah Robinson, Shane McDonnell, Benedicte Duretz, Samuele Scurati

P-25

Analysis of methamphetamine and amphetamine in human plasma using pipette tip solid-phase extraction and high-performance liquid chromatography/tandem mass spectrometry

Akemi Marumo, Takeshi Kumazawa, Xiao-Pen Lee, Masaya Fujishiro, Keizo Sato, Chika Hasegawa

P-26

Analysis of benzodiazepines from urine and whole blood by novel disposable pipette extraction (DPX) coupled to LC/MS/MS

Oliver Lerch, Fred D. Foster, Edward A. Pfannkoch, William E. Brewer, Tom Gluodenis

P-27

GC-MS screening for pesticides in plant material using a novel isolation method based on disposable pipette RP-extraction

Thomas J. Mahier, Athra Al-Shaikh, Mohammed Al-Tufail, Maciej J. Bogusz

Topic: Analytical Toxicology

P-28

Development of a sensitive polyclonal antibody for the detection of dextromethorphan and the main metabolite dextrorphan

M.E. Benchikh, P. Lowry, R.I. McConnell, S.P. Fitzgerald

P-29

Development of polyclonal antibodies for the detection of antidepressants

M. E. Benchikh, P. Lowry, R. I. McConnell, S. P. Fitzgerald

P-30

Development of sensitive polyclonal antibodies for the detection of zaleplon and zolpidem

M. E. Benchikh, P. Lowry, R. I. McConnell, S. P. Fitzgerald

P-31

Development of simultaneous biochip array-based immunoassays for the detection of Z drugs in blood

M. E. Benchikh, P. Lowry, R. I. McConnell, S. P. Fitzgerald

P-32

Development of simultaneous biochip immunoassays for salicylate and salicyluric acid for the effective monitoring of aspirin in urine

M.E. Benchikh, P. Lowry, J. Porter, R.I. McConnell, W. Snelling, S. Fitzgerald

P-33

Simultaneous determination of hallucinogens with Evidence biochip arrays

M. E. Benchikh, P. Lowry, R. I. McConnell, J. Porter, S. P. Fitzgerald

P-34

Measurement of lithium in serum using a colorimetric assay with enhanced stability and sensitivity on the fully automated RX series analysers

T. Lipton, P. McGivern, R. Bell, J. Campbell, S. P. Fitzgerald

P-35

Determination of six drugs of abuse in urine on the RX series analysers with assay kits using multi-analyte calibrators

P. McGivern, E. Donnelly, J. Thompson, R. Bell, J. Campbell, S. Fitzgerald

P-36

Performance characteristics of ten drug of abuse assays using Syva EMIT II Plus reagents adapted to the ADVIA 1200, 1650/1800, and 2400 Chemistry Systems

Richard Edwards, Gena Fischer, Jessica Whalen, Nancy Carmosino, Claus Pruemper, Patrick Cusack, Jose Fernandez

P-37

New Emit® II Plus 6-acetylmorphine assay on the V-Twin®/Viva-E® Analyzers

N. Morjana, H. Yau, A. Dominowski, C. Schaible, Y.F. Zheng, Douglas Clark, Gerald E. Siefring

P-38

Multicenter evaluation of ONLINE DAT Amphetamines II Assay on Roche Hitachi, cobas® Analyzers, and COBAS INTEGRA Systems

Alain Verstraete, I. Rogiers, W. Haase, D. LeGatt, C. Shalapay, J. Collins, R. Setterstrom, C. Beck, I. Domke, Mary Jane Coffing

P-39

Multicenter evaluation of ONLINE DAT Benzodiazepines II Assay on Roche Hitachi, cobas® Analyzers, and COBAS INTEGRA Systems

Alain Verstraete, I. Rogiers, W. Haase, D. LeGatt, C. Shalapay, J. Collins, R. Setterstrom, D-A. Wildbredt, C. Beck, I. Domke, Mary-Jane Coffing

P-40

Five urine specimen validity tests evaluated on automated, high-throughput ADVIA Chemistry Systems, ADVIA 2400, ADVIA 1650/1800, and ADVIA 1200, from Siemens Healthcare Diagnostics

Jian Dai, Jacobson Robert, Cherian Saji, Ming Guo, Claus Pruemper, Algarin Principe, Roseta Sword

P-41

Comparison of concomitant Cedia immunoassay drugs of abuse results in urine and oral fluid samples

Frances Flores, Brian Johns, Felix Norman-Williams, Sally Benton

P-42

Validation of an automated enzyme assay for quantitation of GHB in human serum and urine

Lara Hasan, Michel Scotti, Thomas Jermann, Jakob Weber, Wolfgang Jöchle, Daniel Gygax, André Scholer

P-43

The importance of norbuprenorphine cross-reactivity in a buprenorphine urine immunoassay

Michael Vincent, Guohong Wang, Kim Huynh, James Bourland, Cynthia Coulter, Christine Moore

P-44

Immunobased SPFS biosensor for determination of CRP in serum

Andreas Scholten, Martin Juebner, Markus A. Rothschild, Katja Bender

P-45

Single dose of 267 mg fenofibrate results in false-positive amphetamine and ecstasy screen results in urine

Ayse Parlar, Asl?han Yap?c?, Ahmet Ayer

P-46

Determination of selected antihypertensive drugs in human serum by liquid chromatography-linear ion trap mass spectrometry

Vilma Habrdova, Marcel Bima, Jiri Ceral, Romana Psenickova, Vladimir Palicka, Viktor Vorisek

P-47

Simultaneous screening for 54 toxic alkaloids in blood by liquid chromatography - tandem mass spectrometry

Wei Liu, Min Shen

P-48

An LC-MS method to measure cathinone, norpseudoephedrine and phenylpropanolamine in urine

Samantha King, Molly Zaman, Frances Flores, Sally Benton

P-49

Liquid chromatography - mass spectrometry: an objective and fast diagnostic method for the Amanita muscaria and Amanita pantherina intoxication

Peter Ondra, Barbora Merová, Marie Sta?ková, Jan St?íbrný

P-50

Specific cannabinoid analysis using LC-MS/MS

Jason Causon, Daniel Leigh

P-51

Analysis of drugs of abuse in urine by head-space APCI/ITMS

Masuyoshi Yamada, Takefumi Yokokura, Tsukasa Shishika, Hidetoshi Morokuma, Hiroaki Hashimoto, Masako Ishimaru, Hiroyuki Inoue

P-52

LC-MS study for detection of „Spice“-ingredients in forensic psychiatry

Jörg Teske, Jens-Peter Weller, Urs-Vito Albrecht, Axel Weber

P-53

Elecrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid

Kayoko Minakata, Kunio Gonmori, Hideki Nozawa, Itaru Yamagishi, Sanae Kanno, Koutaro Hasegawa, Kanako Watanabe, Osamu Suzuki

P-54

Measurement of dasatinib and imatinib in human plasma/serum by LC-MS/MS

Michelle Ann Birch, Patty Nooijen, Lewis Couchman, Phillip Edgar Morgan, Aloysius Ho, Robert James Flanagan

P-55

Rapid screening and confirmation of six anticoagulant rodenticides in whole human blood using liquid chromatography tandem mass spectrometry

Hui Yan, Min Shen, Xianyi Zhuo

P-56

Simultaneous determination of 14 oral antidiabetics in human plasma by electrospray ionization liquid chromatography/tandem mass spectrometry

Cornelius Hess, Frank Musshoff, Burkhard Madea

P-57

Screening for and qualification of 20 hypotensive drugs in whole blood by liquid chromatography-tandem mass spectrometry

Bogdan Tokarczyk, Maria Kala

P-58

Validation of an HTLC-MS/MS method for amiodarone and metabolite, and review of patient results

Christine Snozek, Jessica Erbsen, Loralie Langman

P-59

Simultaneous and sensitive analysis of dasatinib, imatinib, norimatinib, and nilotinib in human plasma using Turboflow LC-MS/MS

Lewis Couchman, Patty Nooijen, Michelle Birch, Sarah Robinson, Robert Flanagan

P-60

Ultra-performance liquid chromatographic method for measurement of voriconazole in human plasma

Rafael Linden, Marina Antunes, Paula Boeira, Alessandro Pasqualotto

P-61

Quantitative analysis of 21 benzodiazepine drugs, zolpidem and zopiclone in serum using UPLC/MS/MS

Mark Roberts, Stephanie Marin, Gwen McMillin, Michelle Wood

P-62

Determination of the most frequently used drugs in whole blood by using ultra performance liquid chromatography tandem mass spectrometry (UPLC/MS/MS)

Carolien Boone,Beitske Smink, José Roque, Albert Dijkhuizen

P-63

Stereoselective analysis of venlafaxine and its major metabolites in human plasma and whole blood by liquid chromatography-tandem mass spectrometry

Maria Kingbäck, Martin Josefsson, Louise Karlsson, Johan Ahlner, Finn Bengtsson, Fredrik C. Kugelberg, Björn Carlsson

P-64

Validation and application of a rapid LC-MS/MS method for the enantioselective determination of methadone and EDDP in clinical serum samples

Michael Boettcher, Stefan Lierheimer, Olof Beck

P-65

Turbulent flow chromatography as fast and reliable method for the quantitative determination of antipsychotic drugs with LC-MS/MS

Daniel Mueller, Katharina Rentsch

P-66

LC-TOF screening technique for drugs of abuse – evaluation in authentic patient urine samples

Nicolai Stephanson, Aljona Saleh, Olof Beck

P-67

Identification of remifentanil and its metabolite by LC-quadrupole–time of flight mass spectrometry

Peter Stockham, Amanda Thompson, Heather Felgate, Karen Heath, Peter Felgate

P-68

Screening analysis for drugs dangerous to road safety in whole blood using ultra performance liquid chromatography time-of-flight mass spectrometry (UPLC-TOFMS)

Rasmus Telving, Mette Findal Andreasen

P-69

Determination od Salvinorin A and Salvinorin B in body fluids by LCMS-IT-TOF system

Marie Stankova, Roman Oros, Petr Kurka, Vladimira Gebauerova

P-70

THCVA-A – a new additional marker for illegal cannabis consumption

Lars Radünz, Folker Westphal, Edmund Maser, Gertrud Rochholz

P-71

MRM³ - a highly selective and sensitive technique for the determination of various xenobiotics in complex matrices

Jens Trafkowski, Jan Lembcke, Axel Besa

P-72

Beta-glucuronidase-mediated reduction of temazepam and its glucuronide to diazepam

Shanlin Fu, Peter Bowron, Hongjie Wang, Michael Dawson

P-73

Development of new methods for maninil analysis for forensic - chemical investigation of biological substrates

Mareta Ibragimova, Latif Ikramov

P-74

Oxidation of MDMA in urine after exposure to bleach

Annie Pham, Shanlin Fu, Michael Dawson

P-75

Drug cocktail poisoned twelve people in a psychiatric session: MDMC, MDMA and MDA were identified by the TOX.I.S

Thomas Grobosch, Lucie Dubugnon, Torsten Binscheck

P-76

Structure-retention relationships for basic drugs separated on different GC phases

Linda Glowacki, Dimitri Gerostamoulos, Paul Wynne

P-77

Oxidative adulterants and their influence on the detectability of drugs of abuse in urine by immunoassay and GC-MS

Frank Sporkert, Dorothée Nicolier, Magali Dovat-Sabatella, Marc Augsburger

P-78

Minimising false positive results of ‘Drugs of Abuse’ in urine samples by GC-TOF/MS and novel target identification algorithms

Petra Gerhards, Juergen Sawazki, Pierre Schanen, Gerhard Horner, Luzia Schaaf

P-79

Study of rapid chiral analysis of amphetamines in whole blood by GC-MS – Application of diatomaceous earth extraction

Hiroshi Fujii, Kenji Hara, Mitsuyoshi Kageura, Masayuki Kashiwagi, Aya Matsusue, Shin-ichi Kubo

P-80

Simultaneous quantitation of amphetamines, cannabinoids, cocaines, and opiates in human urine by GC-MS

Jae Chul Cheong, Min Kyoung Kim, SungIll Suh, Yong Jun Suh, Moon Kyo In

P-81

Detection of the synthetic drug 4-Fluoroamphetamine (4-FA) in serum and urine

Jörg Röhrich, Siegfried Zörntlein, Jürgen Becker, Thomas Kaufmann, Reinhard Urban

P-82

Analysis of expanded sympathomimetic amines on single quadrupole GC/MS

Matthew Lambing, Jason Cole, Anton Mayer

P-83

Intoxication with butylone and phenazepam among young cocaine users

Maria Teresa Pinorini-Godly, Frank Sporkert, Markus Schläpfer, Manuel Rusconi, Ario Conti

P-84

High-throughput confirmation and quantitation of a THC metabolite in urine by GC/MS

Matthew Lambing, Jason Cole, Anton Mayer

P-85

Simple and practical sample preparation for detection of triazolam in body material by gas chromatography-negative ion  chemical ionization mass spectrometry

Kenji Hara, Masayuki Kashiwagi, Aya Matsusue, Tomoko Sugimura, Mitsuyoshi Kageura, Shin-ichi Kubo

P-86

Determination of ibotenic acid and muscimol in urine of a person intoxicated with Amanita pantherina

Jan St?íbrný, Miloš Sokol, Barbora Merová, Petr Ondra

P-87

Monolithic spin-column extraction and gas chromatography-mass spectrometry method for the simultaneous assay of diquat, paraquat, and feintrothion in human serum and urine

Takeshi Saito, Akira Namera, Yuko Yui, Shota Miyazaki, Akihira Nakamoto, Sadaki Inokuchi

P-88

Polychlorinated biphenyls in adipose tissue by GC/MS

Mariza Insaurralde, Arlene Schuller, Gustavo Díaz Gill, Renate Díaz Gill, Eleuterio Umpiérrez, Haydee Romero

P-89

Determination of GHB in dried blood spots using a simple GC-MS method

Ann-Sofie Ingels, Willy Lambert, Christophe Stove

P-90

Characterization of pentoxyverine and its metabolites in urine using GC/MS after intoxication with Silomat R cough drops

Jochen Stegk, Folker Westphal, Thomas Junge, Gertrud Rochholz, Andrea Neusüß, Lars Radünz

P-91

Fast and simple HPLC-DAD analysis for TDM of voriconazole

Daniëlle Borrey, Veronique Engelrelst, Eric Nulens, Bart Gordts

P-92

Development of methods for hexamidine isolation and discovery from biological objects while forensic - chemical inrestigation

Jalilov Fazliddin, Mansur Tojiyev

P-93

Internet based computer processing of thin-layer chromatography data in systematic toxicological analysis

Rafael Linden, Estefânio Kellermann

P-94

Analysis of oral antidiabetic drugs by TOXI-LAB's thin-layer chromatographic method

Mareta Ibragimova, Ilhom Akhmedjanov

P-95

Stability of diazepam and bromazepam in various samples at different storage conditions

Vasil Atanasov, Atanas Runiov, Silviya Stoykova, Tsvetelina Dimitrova, Mariana Mitewa

P-96

Does the application of propanols used for hand disinfection affect the congeners analysis?

Harald Below, Elke Below, Britta Bockholdt, Nora Bieber, Thomas Nicolai, Alexander Usche, Ojan Assadian, Günter Kampf, Wolfram Parzefall, Axel Kramer

P-97

Correlation between exhaled carbon monoxide and self-reported smoking status with urinary cotinine

Guilherme Petersen, Laura Marder, Carlos Leite, Julia Machado, Flavia Thiesen, Jose Miguel Chatkin

P-98

Intoxication by thallium

Petr Kurka, Marie Stankova, Jana Kubackova, Vladimira Gebauerova

P-99

Lead exposure - A case study of Indian bangle makers

Yeshvandra Verma, S.V.S. Rana

Topic: Drug Metabolism and Kinetics:

P-100

In vitro metabolism of the emerging drug candidate S107 in preventive doping research

Simon Beuck, Wilhelm Schänzer, Mario Thevis

P-101

Residue and microsomal P450 analysis of ACTP-ester in goat

Chittaranjan Sahu, Biplab Bagchi

P-102

Stereoselective disposition of venlafaxine and its major metabolites in postmortem femoral blood in relation to CYP2D6 polymorphism

Louise Karlsson, Maria Kingbäck, Anna-Lena Zackrisson, Björn Carlsson, Martin Josefsson, Finn Bengtsson, Johan Ahlner, Fredrik Kugelberg

P-103

Analysis of quetiapine metabolites in patient samples using high-performance liquid chromatography/tandem mass spectrometry

Danielle Suzannah Fisher, David Taylor, Phillip Edgar Morgan, Robert James Flanagan

P-104

The metabolism and excretion of quinine by the greyhound

Linda Glowacki, Dimitri Gerostamoulos, Paul Wynne

P-105

Species differences in the metabolism of Phalaris alkaloids

Paul Wynne, Linda Glowacki, Dimitri Gerostamoulos

P-106

Quantification of daptomycin with LC-MS/MS in plasma samples of patients undergoing continuous veno-venous hemodiafiltration

Katharina Rentsch, Ursula Gutteck-Amsler, Natascia Corti, Alain Rudiger, Marco Maggiorini

Topic: Hormones in Doping Control and Forensics

P-107

Validation of a GC/MS method for the detection of two quinolinone-derived selective androgen receptor modulators in doping control analysis

Enrico Gerace, Alberto Salomone, Renzo Costa, Antonella Di Stilo, Marco Vincenti

P-108

Determination of new doping substances by LC–MS/MS using various urine preparation methods

Irina I. Sukhanova, Marina A. Dikunets, Sergey L. Bolotov, Grigory M. Rodchenkov

P-109

Common LC-MS/MS fragment ions of prohibited substances for target and non-target doping analysis

Svetlana Appolonova, Natalia Mesonzhnik, Dasha Brazhnikova, Gregory Rodchenkov

P-110

High resolution and high mass accuracy : A new approach for screening in doping control analysis

Benedicte Duretz, Yves Moulard, Yves Bonnaire, Sarah Robinson, Samuele Scurati

P-111

Development of an automated LC-TOFMS screening method for the identification and confirmation of doping agents in urine

Juan Carlos Domínguez-Romero, Juan Francisco García-Reyes, Antonio Molina-Díaz

P-112

Quantitation of testosterone esters in oil-based injectables with micellar electrokinetic chromatography (MEKC-DAD)

Matthias Balsam, Diana Domke, Thomas Knepper, Michael Pütz

P-113

Possible biomarkers of Synacthen abuse by athletes

Svetlana Appolonova, Grigory Rodchenkov

P-114

Effects of endurance exercise on the urinary proteome analyzed by 2D-PAGE and Orbitrap mass spectrometry

Katja Walpurgis, Maxie Kohler, Andreas Thomas, Markus de Marées, Joachim Mester, Wilhelm Schänzer, Mario Thevis

Topic: Alternative Matrices

P-115

"Peri-analytics" reference ranges for drug screening in oral fluid using the Greiner-Bio-One collection device

Michael Boettcher, Andreas Preidel, Olof Beck

P-116

Performance evaluation of DAT oral fluid amphetamines, methamphetamine, opiates and phencyclidine assays on Roche Hitachi

D. Kuntz, M. Meixner, K. Armstrong, B. Masters, Mary-Jane Coffing, I. Domke, C. Beck

P-117

Investigation of salivary pH after different foods and drinks: Effects on immunoassay screening

Eva Maria Reichardt, Dene Baldwin, David Osselton

P-118

A sensitive method to detect and quantify ?⁹-THC in oral fluid by liquid chromatography-tandem mass spectrometry

Anna Molnar, Shanlin Fu, Philip Doble, John Lewis

P-119

The use of F-SPE/ Fast LC-MSMS for analyzing low level THC in oral swabs

Jeffery Hackett, Albert Elian, Michael Telepchak

P-120

The determination of cathinone in oral fluid by LC-MS-MS as part of a workplace testing program

Peter Akrill, Claire George

P-121

Rapid screening and UPLC/MS-MS toxicological analysis of oral fluid for diagnosis of acute intoxication in emergency

Paola Cassandro, Anna Carfora, D. Di Candia, F. Lodi, C. Volpe, Renata Borriello

P-122

Oral fluid results compared to self reports of recent illicit drug use by methadone maintenance patients

Edward Cone

P-123

Detection of paraquat in oral fluid by capillary electrophoresis for diagnosis of acute poisoning

Rafael Lanaro, José Luiz Costa, Luciane C.R. Fernandes, Marina M.F Tavares, Alice Ap.M Chasin

P-124

Retrospective analyses of immunoassay results in hair

Katrin M Kirschbaum, Caroline Herzfeld, Katrin Graumann, Hans Sachs, Frank Musshoff, Burkhard Madea

P-125

Simultaneous analysis of psychotropic phenylalkyl¬amines in oral fluid by GC/MS with automated SPE

Hyeyoung Choi, Seungkyung Baeck, Moonhee Jang, Hwakyung Choi, Heesun Chung

P-126

Hair testing and self-report of cocaine use

Claudia Vignali, Cristiana Stramesi, Micol Vecchio, Angelo Groppi

P-127

Measurement uncertainty in quantitative segmental analysis of hair for cocaine and benzoylecgonine

Marc LeBeau, Madeline Montgomery, Cynthia Morris-Kukoski, Jason Schaff

P-128

Products of cocaine and hydrogen peroxide reactions

Mark L Miller, Sarah Himes, Madeline A Montgomery, Marc A LeBeau, Roman Aranda IV

P-129

Combined analysis of meconium and maternal hair. A case report

Merja Gergov, Johanna Ristimaa, Ilkka Ojanperä

P-130

A sensitive determination of benzodiazepines in hair and nail with ultra-performance liquid chromatography-tandem mass spectrometry

Rina Kaneko, Azusa Uchida, Tatsushi Mizutani, Tadashi Ogawa, Hideki Hattori, Hiroshi Seno, Osamu Suzuki, Akira Ishii

P-131

Diazepam, nordiazepam and oxazepam in hair samples collected from newborn twins

Wojciech Lechowicz, Roman Stanaszek, Wojciech Piekoszewski, Ewa Florek

P-132

Investigation of the factors affecting endogenous GHB concentrations in human hair

Samar Alzeer, Samar Alzeer, David Watson, Elizabeth Ellis

P-133

Time resolved analysis of quetiapine and 7-OH-quetiapine in hair using LC/MS-MS

Stephanie Teodoro, Serge Schneider, Michel Yegles

P-134

Evidence of Haldol (haloperidol) long-term intoxication

Enrico Gerace, Alberto Salomone, Marco Vincenti, Sergio Pellegrino

P-135

Evaluation of copper levels in hair and liver samples obtained from Wilson’s Disease patients

Serap Annette Akgur, Hasan Ertas, Levent Elibol, Nuri Idiz, Gorkem Yararbas, Ma?allah Baran, Çi?dem Ar?kan, Sema Aydo?du

P-136

Investigation of hair as a marker for the detection of diabetes mellitus

Mareta Ibragimova, Makhmudjon Shakhitov

Topic: Postmortem Toxicology

P-137

Blue pieces of unknown substance in the stomach: An interesting unnatural death investigation

Maria Afxentiou Stylianou, Katerina Liveri, Nantia Kolokassidou, Anna Krashia, Myriam Frantzi, Eleni Procopiou, Popi Kanari

P-138

Intentional suicide by formic acid ingestion

Jennifer Button, Rachael Jones, Frank Tames, Sebastian Lucas, David W. Holt

P-139

A fatal intoxication by chloroprene

Annette Rickert, Bernd Kardel, Johanna Teloh, Benno Hartung, Thomas Daldrup

P-140

Fatal tolperisone poisoning: autopsy and toxicology findings in three suicide cases

Frank Sporkert, Christophe Brunel, Marc Augsburger, Patrice Mangin

P-141

Case report: suicidal ephedrine-caffeine blend ingestion

Viktor Vorisek, Lenka Zatopkova, Lenka Prochazkova, Vladimir Palicka, Vilma Habrdova, Lenka Haklova

P-142

Two fatalities involving pregabalin

Jennifer Button, David Berry, David W. Holt

P-143

Suicide by hanging under the influence of ketamine and ethanol

Ricardo Jorge Dinis-Oliveira, Félix Carvalho, José Alberto Duarte, Ricardo Dias, Teresa Magalhães, Agostinho Santos

P-144

Distribution of embutramide and mebenzonium iodide in a suicidal death after Tanax® injection

Luca Morini, Fulvia Pozzi, Enrico Risso, Claudia Vignali, Angelo Groppi

P-145

Detection of nalbuphine in postmortem samples

Wagdy Abd-elmeged Soliman

P-146

Fatal poisoning with Taxus baccata: Identification of monohydroxy-taxine, monohydroxy-monoacetyl-taxine and monohydroxy-diacetyl-taxine in postmortem specimens by liquid chromatography-electrospray ionization-tandem mass spectrometry

Thomas Keller, Wolfgang Bicker, Fabio Monticelli, Hans Sachs, Thomas Ketterer

P-147

Fatal poisoning with Aconitum napellus extract: Quantification of aconitine and identification of related alkaloids by liquid chromatography – electrospray ionization – tandem mass spectrometry

Wolfgang Bicker, Fabio Monticelli, Hans Sachs, Thomas Ketterer, Thomas Keller

P-148

Death linked to an uncommon fungus: Kombucha

Frédéric Aknouche, Thierry Besnard, Robert Buti, Henri-Pierre Duval, Gérald Quatrehomme

P-149

Comparison of blood-amphetamine concentration in drug poisoning deaths with people arrested for driving under the influence of this stimulant in Sweden

Johan Ahlner, Anita Holmgren, Wayne Jones

P-150

A preliminary investigation on the distribution of cannabinoids in man

Antonia Gronewold, Gisela Skopp

P-151

Estimating the time of last cannabis use from post mortem whole blood ?9-THC and 11-nor-9-carboxy-?9-THC concentrations

Walter Martz

P-152

Determination of venlafaxine in post-mortem whole blood by HS-SPME and GC-NPD

Orthodoxia Mastrogianni, Konstantina Spagou, Teresa Henriques, Diva Violante, Nikolaos Raikos, Georgios Theodoridis, Athanasios Pouliopoulos, Antonios Tzikas, Konstantinos Psaroulis, Fotios Chatzinikolaou, Elisavet Thessalonikeos, Heleni Tsoukali

P-153

Highly sensitive UFLC-MS/MS analysis of fentanyl and norfentanyl in different post-mortem matrices: seven forensic case studies

Ruth Verplaetse, Eva Cuypers, Coralie Silvestre, Dieter Waumans, Jan Tytgat

P-154

Quantification in post-mortem blood, and identification in urine, of tramadol and its two main metabolites in two cases of lethal tramadol intoxication

Benjamin De Backer, Françoise Renardy, Raphaël Denooz, Corinne Charlier

P-155

Concentrations of morphine, codeine and 6-monoacetyl morphine in femoral blood in heroin-related deaths compared with apprehended drivers

Anita Holmgren, Johan Ahlner, Alan Wayne Jones

P-156

An UPLC-MS/MS method for the determination of valproic acid in blood of a fatal case of intoxication

Paula Proença Cunha, João Miguel Franco, Carla Mustra, Mariana Marcos, Ana Rita Pereira, Francisco Corte-Real, Duarte Nuno Vieira

P-157

The Lady in the Bath Water: A Propofol Assisted Death

William Allender, Stuart Anderson, Susan Jennings and Judy Perl

P-158

Evaluation of carboxyhemoglobin in carbonized victims submitted to postmortem examination at the Institute of Legal Medicine of Sao Paulo, Brazil

Vilma Leyton, Maria de Lourdes SC Strombech, Mario Jorge Tsuchiya, Paulo Dirceu Luchini, Jose Arnaldo Soares-Vieira, Julio Ponce, Daniel Romero Muñoz

P-159

Quantitative analysis of methadone and EDDP in a single puparial case of blowflies (Diptera, Calliphoridae, Lucilia sericata,) using UPLC-MS/MS

Matthias Gosselin, Vincent Di Fazio, Sarah M. R. Wille, Nele Samyn, Benoit Bourel, Pierre Rasmont

P-160

Deaths involving selective serotonin reuptake-inhibitors

Jennifer L. Pilgrim, Dimitri Gerostamoulos, Olaf H. Drummer

P-161

A five years retrospective study of acute poisoning cases investigated by The Forensic Laboratory of Ministry of Justice in Upper Egypt

Nady Sayed Aly

P-162

Twenty years of heroin-related death statistics: how the Victorian drug scene has changed

Jessica Woods, Dimitri Gerostamoulos, Olaf Drummer

P-163

Presence of ethanol in suicidal deaths: a 12 year study in Epirus, North-western Greece

Vassiliki Boumba, Kleo Fragkouli, Theodore Vougiouklakis

P-164

The impact of post-mortem redistribution on the blood concentrations of therapeutic drugs

Pierre-Yves Tremblay, Michel Lefebvre, Lyse Lefebvre

P-165

Microbial ethanol production: Experimental study and multivariate evaluation

Vassiliki Boumba, Vangelis Oikonomou, Nikos Kourkoumelis, Panagiota Gousia, Chrissanthy Papadopoulou, Theodore Vougiouklakis

P-166

Genetic analysis of rhabdomyolysis-associated genes and immunohistochemical study of myoglobin in the kidney in autopsy cases of methamphetamine abusers

Aya Matsusue, Kenji Hara, Masayuki Kashiwagi, Mitsuyoshi Kageura, Tomoko Sugimura, Shin-ichi Kubo

Topic: Forensic Chemistry

P-167

Identification of 1-butyl-3-(1-(4-methyl)naphthoyl)indole in a “SPICE”-like herbal mixture

Folker Westphal, Frank Sönnichsen, Simone Thiemt

P-168

Identification of new synthetic cannabinoids in herbal mixtures

Wonkyung Yang, Sanggil Choe, Youran Park, Hwakyung Choi, Heesun Chung

P-169

Non-Cannabinoids: identification of CB1 and CB2 selective ligands in an herbal blend (Mojo)

Marilisa Ferri, Roberto Mencarelli, Federica Mentrasti, Raffaele Giorgetti, Adriano Tagliabracci

P-170

GC-MS detection and quantification of the non traditional cannabinoids JWH-018 and JWH-073 in a commercial herbal mixture

Jennifer Pascali, Claudia Rimondo, Giovanni Serpelloni, Franco Tagliaro

P-171

Applications of desorption-electrospray-ionization-mass spectrometry (DESI-MS) in forensic toxicology

Christoph Härtel, Michael Pütz, Nathalie Martin, Uwe Karst

P-172

Direct analysis of cannabis by thermal desorption counter-flow introduction atmospheric pressure chemical ionization mass spectrometry

Hiroyuki Inoue, Hiroaki Hashimoto, Susumu Watanabe, Yuko T. Iwata, Kenji Tsujikawa, Tatsuyuki Kanamori, Hajime Miyaguchi, Kenji Kuwayama, Takefumi Yokokura, Masuyoshi Yamada

P-173

Characteristics of cannabinoids composition of Cannabis plants grown in Northern Thailand and its forensic application-Part II: second generation studies

Prapatsorn Tipparat, Dr.Surapol Natakankitul, Pipop Chamnivikaipong, Sirot Chutiwat

P-174

Standardised analysis of cannabis products for the determination of the total ?⁹-THC content

Franz Dussy, Luginbuehl Marco, Thomas Briellmann

P-175

Organic adulterants present in crack´s seizure of São Paulo - Brazil

André Fucushima, Alice Chasin, Virgínia Carvalho, Débora Carvalho, Ernesto Diaz, Mariana Portugal

P-176

Purity of “Street” ketamine preparations retrieved from night club amnesty bins in London

Eva Maria Reichardt, John Ramsey, David Osselton

P-177

Impurity profiling of methamphetamine by cross-matching test using liquid-liquid extraction and automated solid-phase microextraction

Jaesin Lee, Yonghoon Park, Heesun Chung, Hiroyuki Inoue, Kenji Kuwayama, Eunmi Kim, Yujin Park, Jeonghill Park

P-178

Online availability of designer drugs: Do you get what you pay for?

Susannah Davies, Gareth Smith, David Wood, Jennifer Button, John Ramsey, David W. Holt, Paul I. Dargan

P-179

Judicial-chemical research of some neuroleptics

Roman Kalekin, Evgenie Salomatin, Viktoria Kalekina, Alla Volkova

P-180

Simultaneous analysis of alpha-amanitin, beta-amanitin and phalloidin in toxic mushrooms by liquid chromatography coupled to time-of-flight mass spectrometry

Walid Ahmed, Kunio Gonmori, Masako Suzuki, Hideki Nozawa, Itaru Yamagishi, Sanae Kanno, Koutaro Hasegawa, Kayoko Minakata, Kanako Watanabe, Osamu Suzuki

P-181

Determination of atropine and scopolamine contents in Datura wrightii, an ornamental plant often present in public parks

Patrick Mura, Sarah Chollet, Bertrand Brunet

P-182

Standardized GC-MS (EI) procedure for monitoring the detection and identification performance applied to herbal remedies

Thomas J. Mahier, Inaam J. Al-Doush, Athra Al-Shaikh, Mohammed Al-Tufail, Maciej J. Bogusz

Topic: Alcohol Markers

P-183

Implementation of ultra-high resolution mass spectrometer ExactiveTM for analysis of EtG and EtS in human urine

Kent Johnson, Marta Kozak

P-184

Extraction of ethyl glucuronide (EtG) using a new resin-based mixed-mode strong anion exchange SPE sorbent prior to LC-MS/MS analysis

Rhys Jones, Lee Williams, Helen Lodder, Steve Jordan, Steve Plant, Richard Calverley, Claire Desbrow, Gary Dowthwaite

P-185

Optimizing the detection of alcohol consumption: Screening for urinary ethyl glucuronide in addition to common alcohol markers in the blood

Hilke Andresen, Niels Tobias, Stefanie Iwersen-Bergmann, Alexander Mueller, Bjoern Nashan, Martina Sterneck, Katharina Staufer

P-186

Determination of ethyl glucuronide in hair samples of Chinese people by large volume injection- gas chromatography-tandem mass spectrometry?LVI-GC/MS/MS?

Baohua Shen, Yan Shi, Hui Yan, Ping Xiang, Min Shen

P-187

Carbohydrate Deficient Transferrin (CDT) is effective in identifying alcohol abuse also below the usual reference limits. Re-assessment of the reference limit

Federica Bortolotti, Daniela Sorio, Franco Tagliaro

Topic: Recent Developments in LC-MS Screening

P-188

Determination of acidic and neutral therapeutic drugs in human blood by liquid chromatography-electrospray tandem mass spectrometry

Lambert K. Sorensen

P-189

Unknown screening for toxic compounds and drugs in plasma and urine based on LC-MS/MS

Samuele Scurati, Cecilia Gechtman, Benedict Duretz, Sarah Robinson, Adriano Masarin

P-190

Evaluation of two alternative UPLC-MS approaches as potential replacements for the REMEDi HS drug profiling system

Michelle Wood, Robert Lee, Mark Roberts, Nayan Mistry

P-191

Toxicological screening of basic drugs in whole blood using a new UPLC-QTOF-MS method

Petur Weihe Dalsgaard, Brian Schou Rasmussen, Kristian Linnet

P-192

Development and practical application of a CID mass spectra library of toxic compounds for systematic toxicological analysis by LC-QTOF-MS

Sebastian Broecker, Sieglinde Herre, Bernhard Wuest, Fritz Pragst

P-193

A comparison of methods for the determination of xenobiotics in biological samples: Multiple Reaction Monitoring (MRM) vs. General Unknown Screening (GUS)

Brad Patterson, Jochen Beyer, Dimitri Gerostamoulos, Olaf Drummer

P-194

Development of an automated MS-based screening procedure for clinical and forensic toxicology

Jürgen Kempf, Susanne Vogt, Sebastian Götz, Birgit Schneider, Petra Decker, Anna Sandhaas, Wolfgang Weinmann, Carsten Baessmann

P-195

Comparison of forensic multi-target screening and unknown screening on an LC/MS/MS system with automatic library searching for compound identification

Jens Trafkowski, Pauline Vollmerhaus, André Schreiber

P-196

Optimizing library search performances for LC-MSMS: SmileMS to cope with spectral variability and instrumentation heterogeneity

Pierre-Alain Binz, Roman Mylonas, Yann Mauron, Annette Jordan, Bernard Favrat, Marc Augsburger, Alexandre Masselot, Nicolas Budin

Various Topics

P-197

MDMA and MDA induced oxidative stress in brains of mice

Luka Marumo, Sachiko Tanaka, Satoshi Numazawa, Takemi Yoshida

P-198

Effects of synthetic cannabinoids on electroencephalogram power spectra in rats

Nahoko (Otani) Uchiyama, Ruri Kikura-Hanajiri, Naomi Matsumoto, Zhi-Li Huang, Yoshihiro Urade, Yukihiro Goda

P-199

Evaluation of the efficacy of the aqueous extract of Senna occidentalis in the amelioration of tetracycline-induced hepatotoxicity and nephrotoxicity in rabbits

Gafer Ahmed, Melanie Abongwa, Oluwadamilola Arowolo

P-200

Workplace drug testing performed in Naples (Italy) between 2000-2009

Renata Borriello, Anna Carfora, Anna Cucciardi, Raffaella Petrella, Luisa Russello, Paola Cassandro

P-201

Prevalence of drug abuse amongst workers in Italy. Results and evaluations after the recent enforcement of the National Workplace Drug Testing Law

Isabel Kazanga, Silvia Tameni, Alberto Piccinotti, Ivan Floris, Gabriele Zanchetti, Aldo Polettini

P-202

Hospital effluents as a problematic source of anthropogenic metals

Jean-Pierre Goullé, Christian Lacroix, Elodie Saussereau, Loïc Mahieu, Dominique Cellier, Joël Spiroux, Michel Guerbet

P-203

The usefulness of commercial quantitation software in ibogaine LC-MS/MS analyses

Gordana Koželj

P-204

Reference materials for drugs of abuse testing in pharmaco-toxicology: freeze-dried urine samples

Simona Pichini, Stefano Bompadre, Francesco Brandimarti, Raffaele Giorgetti

P-205

The accuracy profile: a universal and essential tool in forensic toxicology

Aurélien Thomas, Julien Déglon, Estelle Lauer, Christèle Widmer, Christian Staub

P-206

An acute case of intoxication with Microcystin in recreational water in Argentina. Clinical parameter and interrelation with the exposure to Microcystin-LR in mice

L. Giannuzzi, D. Sedan, D. Andrinolo, L. Telese